A sys­tem (algo­rithm) deve­lo­ped by the ZKRD for cal­cu­la­ting the ulti­ma­te pro­ba­bi­li­ty of fin­ding a match for a pati­ent among incom­ple­te­ly typed donors based on know­ledge of the gene­tic make­up of a popu­la­ti­on (cal­led haplo­ty­pe frequencies).